PURPOSE: To examine the evidence of the impact of cognitive-behavioral therapy (CBT) on suicide risk in adolescents. METHOD: PubMed, Embase, and CINAHL were systematically searched. A priori inclusion criteria specified randomized controlled and quasi-experimental studies (published 2013 to 2023) in English, with participants aged 11 to 24 years. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and structured quality appraisals were used to ensure rigor. Studies evaluated CBT's effectiveness in reducing suicidal ideation/attempts. RESULTS: Studies ( CONCLUSION: CBT is a safe and effective intervention for reducing suicide risk in adolescents. Findings support its potential as an approach for youth, with further research needed to explore long-term outcomes and diverse populations. [