Effect of adjuvant cisternostomy on the prognosis of patients with severe traumatic brain injury: A single center's retrospective study.

• Tác giả: Peng Chen, Shiqi Cheng, Daokun Shu, Bin Wang, Wei Wang, Dongdong Xu, Raorao Yuan, Qiquan Zhang, Wenxin Zheng, Yi Zhuo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 133.594 Types or schools of astrology originating in or associated with a
• Thông tin xuất bản: United States : Medicine , 2025
• Bộ sưu tập: NCBI
• ID: 695043

Tóm tắt

 This study evaluates the efficacy of adjuvant cisternostomy (AC) versus decompressive craniectomy (DC) in managing severe traumatic brain injury (sTBI). A single-center retrospective analysis of consecutive sTBI patients treated with AC or DC alone (2018-2019) revealed that the AC group exhibited significantly lower intracranial pressure and higher Glasgow Coma Scale scores compared with the DC group (P <
  .05). Cerebrospinal fluid and serum analyses demonstrated reduced interleukin-1β and nerve fiber layer levels in the AC group. In addition, the AC group required lower mannitol dosages and showed fewer postoperative complications. Six-month follow-up indicated a statistically higher rate of good prognosis in the AC group (P <
  .05). These findings suggest that AC is superior to DC in reducing intracranial pressure, mitigating neurological damage, and improving clinical outcomes in sTBI patients.