P21-Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy.

• Tác giả: James Bae, Tangting Chen, Yu He, Christopher L-H Huang, Huan Lan, Ming Lei, Tao Li, Yangpeng Li, Leiying Liu, Ting Liu, Zhu Liu, Xian Luo, Xianhong Ou, Xiaoqiu Tan, Juyi Wan, Xin Wang, Yan Wang, Yan Wei, Chunxiang Zhang, Dan Zhang, Fang Zhao
• Ngôn ngữ: eng
• Ký hiệu phân loại: 181.4 *India
• Thông tin xuất bản: Germany : Advanced science (Weinheim, Baden-Wurttemberg, Germany) , 2025
• Bộ sưu tập: NCBI
• ID: 695047

Tóm tắt

Ventricular arrhythmias associated with cardiac adrenergic stress and hypertrophy pose a significant clinical challenge. We explored ventricular anti-arrhythmic effects of P21-activated kinase 2 (Pak2), comparing in vivo and ex vivo cardiomyocyte-specific Pak2 knockout (Pak2