Exploring the "chemo" in chemoimmunotherapy for triple-negative breast cancer.

• Tác giả: Leif W Ellisen, Ting Liu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 598.634 *Tetrao
• Thông tin xuất bản: United States : Cancer cell , 2025
• Bộ sưu tập: NCBI
• ID: 695627

Tóm tắt

In this issue of Cancer Cell, Zhang et al. use single-cell RNA sequencing to compare immune cell dynamics in triple-negative breast cancers treated with the PD-L1 inhibitor atezolizumab plus paclitaxel or nab-paclitaxel. They identify distinct T cell activation patterns and highlight mast cells' role in immune activation exclusively in the nab-paclitaxel combination.