Polycomb-mediated transgenerational epigenetic inheritance of

• Tác giả: Maximilian Fitz-James, Christopher Paton, Peter Sarkies, Poppy Sparrow
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.453 Tin
• Thông tin xuất bản: England : Open biology , 2025
• Bộ sưu tập: NCBI
• ID: 695706

Tóm tắt

 Transgenerational epigenetic inheritance (TEI) describes the process whereby distinct epigenetic states are transmitted between generations, resulting in heritable gene expression and phenotypic differences that are independent of DNA sequence variation. Chromatin modifications have been demonstrated to be important in TEI
  however, the extent to which they require other signals to establish and maintain epigenetic states is still unclear. Here we investigate whether small non-coding RNAs contribute to different epigenetic states of the Fab2L transgene in