Irreversible electroporation combined with PD-L1/IL-6 dual blockade promotes anti-tumor immunity via cDC2/CD4

• Tác giả: Wenguo Cui, Wei Huang, Yuyue Jiang, Chaojie Li, Tiankuan Li, Jingjing Liu, Xiaoyu Liu, Zilong Qiu, Qungang Shan, Zhongmin Wang, Ziyin Wang, Tao Wei, Chenlei Wen, Zhuozhuo Wu, Ziyu Yang, Yaping Zhuang
• Ngôn ngữ: eng
• Thông tin xuất bản: Ireland : Cancer letters , 2025
• Bộ sưu tập: NCBI
• ID: 695873

Tóm tắt

Pancreatic ductal adenocarcinoma (PDAC) is a "cold" solid tumor with frequent Major Histocompatibility Complex I (MHC-I) deficiency, thereby making it resistant to type-1-conventional dendritic cell (cDC1)-CD8