Alternative treatment for recurrent keloids: initial clinical experience with Rhenium-188 using a specialized device.

• Tác giả: Shannon Brown, Cecilia Corbett, Gerhard Dahlhoff, Martin Magwaza, Thabiso Moeng, Kgomotso M G Mokoala, Linda Nonjola, Mike Machaba Sathekge, Nicholas Vetter, Mariza Vorster
• Ngôn ngữ: eng
• Ký hiệu phân loại: 532 Fluid mechanics Liquid mechanics
• Thông tin xuất bản: Germany : European journal of nuclear medicine and molecular imaging , 2025
• Bộ sưu tập: NCBI
• ID: 696590

Tóm tắt

INTRODUCTION: Keloids have proved challenging to manage with various therapies providing variable success rates and recurrences. Alternative therapies or a multimodal approach is often necessary to ensure complete eradication and prevent recurrence. The use of radioactive creams or patches embedded with Holmium-166, Phosphorus-32 for superficial skin lesions has been documented to be safe and effective. The use of Rhenium-188 has proved effective in non-melanoma skin cancers. We report on the initial experience with Rhenium-188 SCT in the treatment of recurrent keloid lesions. METHODS: Patients with recurrent keloid lesions were recruited for therapy with Rhenium-188. These patients had failed most forms of therapy including surgery, intralesional steroids and radiation therapy. Treatment with RESULTS: A total of 58 lesions were treated. Majority of the lesions were in the head and neck region. The smallest area for treatment was 0.25cm CONCLUSION: Treatment with CLINICAL TRIAL NUMBER: Not applicable.