BACKGROUND: Asthma is associated with an increased risk of cardiovascular mortality, potentially influenced by dietary phosphorus intake through its effects on inflammation and oxidative stress. METHODS: Data from 7,539 asthma patients in the National Health and Nutrition Examination Survey (NHANES) 1999-2018 cohort were analyzed using weighted Cox proportional hazards models to estimate hazard ratios (HR) and 95% confidence intervals (CI). Kaplan-Meier survival curves and a nomogram were used to assess survival probabilities and individualized risk, while restricted cubic spline (RCS) analysis evaluated non-linear dose-response relationships. Sensitivity analyses were conducted to test the robustness of the findings. RESULTS: Higher dietary phosphorus intake was associated with reduced cardiovascular mortality (HR: 0.43
95% CI: 0.22-0.85 for the highest vs. lowest quartile
CONCLUSION: Elevated dietary phosphorus intake is associated with reduced cardiovascular mortality in asthma patients, suggesting its potential as a dietary intervention.