Glycyrrhizin enhances the antitumor activity of cisplatin in non‑small cell lung cancer cells by influencing DNA damage and apoptosis.

• Tác giả: Wenqi Fu, Siying Hu, Jinghan Jiang, Zhufeng Tong, Zhen Wang
• Ngôn ngữ: eng
• Thông tin xuất bản: Greece : Oncology letters , 2025
• Bộ sưu tập: NCBI
• ID: 697667

Tóm tắt

The objective of the present study was to elucidate the mechanism by which glycyrrhizin enhances the antitumor activity of cisplatin in non-small cell lung cancer. Initially, A549 cells were treated with different concentrations of glycyrrhizin (0.25-8 mM) or cisplatin (10-160 µM) for 48 h to investigate the effect of glycyrrhizin combined with cisplatin on A549 cells