Integrated multi-biomarker panel of CXCL13, HS-CRP, and WBC counts predicts outcomes in stroke neurosyphilis patients treated with HBO and TUS-NMES.

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Tác giả: Ruyang Chen, Shuangshuang Chen, Jun Dai, Fanghua He, Wenchao He, Na Lei, Xinyi Shan, Minzhi Wu, Yating Xv, Dan Zhang, Jun Zhang, Xuehua Zhang, Wenhui Zheng, Fengfeng Zhu

Ngôn ngữ: eng

Ký hiệu phân loại: 969.6 +Seychelles

Thông tin xuất bản: Switzerland : Frontiers in neurology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 697802

BACKGROUND: Neurosyphilis results from OBJECTIVE: This study evaluates the predictive value and clinical significance of CXCL13, WBC, and Hs-CRP levels in neurosyphilis patients undergoing HBO and TUS-NMES therapy. METHODS: The study included 158 neurosyphilis stroke patients treated from June 2022 to January 2024. Assessments of limb motor, cognitive functions, daily living abilities, and cerebrospinal fluid biomarkers were conducted pre- and post-four weeks of combined therapy. RESULTS: After treatment, there was a significant improvement in FMA, MoCA, and MBI scores ( CONCLUSION: HBO and TUS-NMES significantly enhance recovery in neurosyphilis stroke patients. CXCL13, WBC, and Hs-CRP effectively predict rehabilitation outcomes, highlighting their value in clinical management.
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