Case Report: Prepubertal-type testicular teratoma with local metastasis in a postpubertal patient.

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Tác giả: Emmanuel S Antonarakis, Pegah Dejban, Michelle Dolan, Olivia C Ghirardelli Smith, Paari Murugan, Andrew C Nelson, Alexander K Tsai, Minghao Zhong

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Frontiers in oncology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 698171

INTRODUCTION: We report for the first time a case of a postpubertal patient presenting with a metastatic prepubertal-type testicular teratoma. CASE DISCUSSION: A 29-year-old male with a history of corrected unilateral cryptorchidism presented with progressive bilateral lower extremity edema. Imaging revealed an inferior vena cava thrombus associated with a complex mass. A left testicular ultrasound identified a solid lesion suggestive of a germ cell tumor, leading to a left radical orchiectomy, which revealed a mature pure teratoma with no evidence of germ cell neoplasia CONCLUSION: This case illustrates that pure mature teratomas lacking chromosome 12p abnormalities, GCNIS, and other dysgenetic features, occurring in postpubertal males, cannot invariably be classified into the benign prepubertal-type teratoma category. Contrary to current paradigm, in rare cases these may represent tumors with metastatic potential.
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