PedBE age and age acceleration in umbilical vein endothelial cells: an examination of infant birth outcomes.

• Tác giả: Raquel G Hernandez, Cathrine Hoyo, Sara B Johnson, Susan K Murphy, Gang Peng, Radhika S Raghunathan, David W Sosnowski, Kristin M Voegtline
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Journal of developmental origins of health and disease , 2025
• Bộ sưu tập: NCBI
• ID: 698244

Tóm tắt

The current study examines the application of the Pediatric-Buccal-Epigenetic (PedBE) clock, designed for buccal epithelial cells, to endothelia. We evaluate the association of PedBE epigenetic age and age acceleration estimated from human umbilical vein endothelial cells (HUVECs) with length of gestation and birthweight in a racially and ethnically diverse sample (analytic sample