Feasibility of telephone and computerized cognitive testing as a secondary outcome in an acute stroke clinical trial: A mixed methods sub-study of the AcT Trial.

• Tác giả: Mohammed Almekhlafi, Ramana Appireddy, Fouzi Bala, Morgan Barense, Brian H Buck, Shelagh B Coutts, Katie N Dainty, Thalia S Field, Aravind Ganesh, Michael D Hill, MacKenzie Horn, Gary Hunter, Houman Khosravani, Krista L Lanctot, Jennifer Mandzia, Alejandro Manosalva, Bijoy K Menon, Adrian M Owen, Pugaliya Puveendrakumaran, Tolulope Sajobi, Michel Shamy, Muzaffar Siddiqui, Nishita Singh, Sajeevan Sujanthan, Richard H Swartz, Aleksander Tkach, Heather Williams
• Ngôn ngữ: eng
• Thông tin xuất bản: England : European stroke journal , 2025
• Bộ sưu tập: NCBI
• ID: 698344

Tóm tắt

 INTRODUCTION: Post-stroke cognitive impairment is associated with impaired quality of life. Remote testing provides a potential avenue to measure cognitive outcomes efficiently. PATIENTS AND METHODS: Prospective cognitive outcomes were collected at 90-180 days using both telephone MoCA (T-MoCA
  range 0-22
  <
 17 impairment) and Creyos, a computerized cognitive battery. Key variables associated with completion were assessed using logistic regressions. Mixed methods brief structured interviews and exit survey were performed to explore barriers to completing computer testing. RESULTS: Of 791 potentially eligible patients (mean age 70 ± 14 years), there was low feasibility of remote cognitive testing, with only 401 (51%) completing the T-MoCA, and 242 (31%) completing Creyos. Our regression models show that age (OR DISCUSSION: Remote cognitive testing has limited feasibility as a secondary outcome in large acute stroke trials. Patients who are older, with worse quality of life, or severe functional impairment post-stroke are less likely to complete remote cognitive outcomes. CONCLUSION: Innovative approaches to post-stroke cognitive outcomes in acute stroke trials are needed.Data AccessData available upon request.