Cognitive performance is associated with return to work after ischemic stroke in young adults: The ODYSSEY study.

• Tác giả: Renate M Arntz, Esther M Boot, Paul Jam Brouwers, Paul Lm de Kort, Karlijn F de Laat, Frank-Erik de Leeuw, Tom den Heijer, Merel S Ekker, Rob Ar Gons, Maikel Hm Immens, Roy Pc Kessels, Anne Mertens, Paul J Nederkoorn, Mijntje Mi Schellekens, Anil M Tuladhar, Mayte E van Alebeek, Ido R van den Wijngaard, Gert W van Dijk, Anouk Gw van Norden, Robert J van Oostenbrugge, Frank G van Rooij, Julia H van Tuijl, Inge Wm van Uden, Marian Sg van Zagten, Esmée Verburgt, Jamie I Verhoeven, Sarah E Vermeer, Marieke Jh Wermer
• Ngôn ngữ: eng
• Ký hiệu phân loại: 373.236 Lower level
• Thông tin xuất bản: England : European stroke journal , 2025
• Bộ sưu tập: NCBI
• ID: 698348

Tóm tắt

 INTRODUCTION: Limited data exist on cognitive performance and return to work after ischemic stroke, especially in patients under 50 years. We investigated whether cognitive performance in the subacute phase after ischemic stroke in young adults was associated with unemployment and the inability to retain their jobs among those who returned to work. PATIENTS AND METHODS: We conducted a multicenter prospective cohort study between 2013 and 2021, enrolling patients aged 18-49 years with first-ever ischemic stroke. Cognitive assessments were performed within 6 months following the index event, covering seven cognitive domains. We categorized patients with cognitive impairment ( RESULTS: Of 525 patients (median age 44.3 [IQR 38.0-47.4] years
  243 women [46.3%])
  median follow-up of 6.6 [IQR 4.5-8.2] years), 426 patients (81.1%) returned to work. Sixty-five patients (15.3%) were unable to maintain employment. In multivariable logistic regression analysis, major VCD (OR = 2.0
  95% CI 1.3-3.0
  DISCUSSION AND CONCLUSION: In young patients after a first-ever ischemic stroke, major VCD and impaired processing speed in the subacute phase after stroke were independently associated with unemployment, but not with the inability to maintain employment.