An assessment of synthesis technique for porous nano and micro fibrous wound dressings with natural oil supplements.

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Tác giả: Meltem Kum, Levent Sendogdular, Selda Topcu Sendogdular

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : Journal of applied biomaterials & functional materials , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 698832

 For millennia, aloe vera (AV) and eucalyptus oil (EO) have been recognized as natural sources of healing and have been utilized for medicinal purposes in the realm of health. As an attempt to treat pressure sores, AV and eucalyptus oil were added as supplements to biocompatible and biodegradable poly (ethylene oxide) (PEO) polymer to synthesize nano and micro fibrous wound dressings by the electrospinning process. Additive solubility in polymeric matrix is the key parameter to achieve the synthesis of homogeneous fibers with controlled release of therapeutic oils, cure and humidity
  therefore, lecithin as herbal (soybean) based emulsifier was used to control additive/polymer solubility. In this study, fibrous dressing in mat form with antioxidant activity was successfully obtained with the addition of natural AV and EO in PEO polymer solutions through electrospinning technique. Subsequently, the synthesized fibers were examined via scanning electron microscopy (SEM), thermogravimetric analysis (TGA), moisture absorption and UV-Vis spectroscopy. SEM imaging demonstrated the formation of randomly-oriented and beadless fibers with size of 0.48 ± 0.23 µm out of PEO/AV/EO/Lecithin blend and also with the addition of lecithin, fiber thicknesses were observed to be increasing. Moisture absorption analysis revealed that the weight of fibrous mat was affected by the humidity of the ambient environment. Relative humidity for 7 days ranged between 32% and 37% and it was observed that lecithin content increased the moisture retention rate by 50%. Uv-Vis results suggested that a more regular performance has been achieved with lecithin being involved in terms of timely manner changes
  therefore, the contrast of samples between hours and days became more distinctive. PEO/AV/EO/Lecithin nanofiber also indicated antibacterial ability against
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