Impact of tacrolimus on interferon gamma ELISpot assay results for the assessment of T-cell immunity: Proof-of-concept.

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Tác giả: Pauline Dessaud, Xavier Fonrose, Raphaële Germi, Thomas Jouve, Patrice Morand, Lionel Rostaing, Françoise Stanke-Labesque, Aurélie Truffot, Jules Weinhard

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : International journal of immunopathology and pharmacology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 698849

Thêm vào giỏ Liên kết toàn văn

SOT patients require immunosuppressors to avoid graft rejection. Therapeutic drug monitoring is insufficient to find the optimal balance with immunosuppression. The evaluation of cell-mediated immunity by enzyme-linked immunospot (ELISpot) assay enumerating interferon-gamma (IFN-γ) is increasingly use. ELISpot assays are performed on peripheral blood mononuclear cells (PBMC) isolated from blood and brought into contact with specific peptides in an immunosuppressor-free environment. This study aims to determine the

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