Lifetime classic psychedelic use and headaches: A cross-sectional study.

• Tác giả: Zusanna Bjurenfalk, Alva Cosmo, Caroline Ran, Otto Simonsson
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Journal of psychopharmacology (Oxford, England) , 2025
• Bộ sưu tập: NCBI
• ID: 698909

Tóm tắt

BACKGROUND: Migraine and cluster headache are two primary headache disorders for which conventional treatments are limited. Classic psychedelic substances such as lysergic acid diethylamide (LSD) and psilocybin are potentially promising new treatment candidates for these conditions. AIMS: The aim of the present study was to investigate the possible relationship between the lifetime use of classic psychedelics and frequent bad headaches in a large British cohort sample. METHODS: Using data ( RESULTS: Lifetime use of classic psychedelics was associated with 25% lower odds of having frequent bad headaches (adjusted odds ratio = 0.75, 95% CI: 0.59-0.95, CONCLUSIONS: The results of the present study add to the literature suggesting classic psychedelics as a possible future prophylactic treatment option for primary headache disorders.