Targeting RNA Polymerase I in Ewing Sarcoma Treatment.

• Tác giả: Gavin Anchondo, Alexis Bruce, Rebekah Carter, Elizabeth Cortez, Sergio Guerrero Pacheco, Hema Sri Kambala, Kyra Parker, Le Su
• Ngôn ngữ: eng
• Ký hiệu phân loại: 616.65 *Diseases of genital system
• Thông tin xuất bản: England : Cancer science , 2025
• Bộ sưu tập: NCBI
• ID: 699436

Tóm tắt

Pharmacologic inhibition of RNA polymerase I activity represents a new therapeutic approach for Ewing sarcoma. This is the first time key components of the ribosome biogenesis pathway have been linked to Ewing sarcoma biology.