Amyloid Deposition Mainly Localized in the Basal Area of the Left Ventricle in a Patient with Amyloid Transthyretin Cardiac Amyloidosis.

• Tác giả: Shuji Arakawa, Satoki Fukae, Kensuke Fukui, Ryosuke Iwasaki, Hiroaki Kawano, Takashi Kudo, Hirokazu Kurohama, Koji Maemura, Kaishi Otsuka, Asumi Takei, Tsuyoshi Yoshimuta
• Ngôn ngữ: eng
• Ký hiệu phân loại: 354.765 +Automotive transportation
• Thông tin xuất bản: Japan : Internal medicine (Tokyo, Japan) , 2025
• Bộ sưu tập: NCBI
• ID: 699773

Tóm tắt

A 74-year-old Japanese man was admitted to our hospital for catheter ablation of paroxysmal atrial fibrillation. Transthoracic echocardiography revealed basal interventricular septal hypertrophy without apical sparing. Cardiac magnetic resonance imaging revealed late gadolinium enhancement in the hypertrophic lesions. The Kumamoto criteria was one point, and the patient had no carpal tunnel syndrome. However, technetium-99m pyrophosphate scintigraphy revealed an accumulation in the basal region of the left ventricle. A skin biopsy revealed transthyretin (TTR) amyloid deposition. A TTR gene examination revealed no variants. This case suggests that amyloid deposition in TTR may occur in the basal area of the interventricular septum.