Efficient synthesis and evaluation of therapeutic potential of fluorine containing 2-arylchromen-4-ones.

• Tác giả: Denis Babkov, Natalia Boltneva, Sergey Cheresiz, Matvey Chertenkov, Iana Esaulkova, Umida Ibragimova, Shokhrukh Khasanov, Nadezhda Kovaleva, Roman Litvinov, Galina Makhaeva, Maria Niukalova, Andrey Pokrovsky, Mikhail Pokrovsky, Larisa Politanskaya, Elena Rudakova, Olga Serebryakova, Nadezhda Troshkova, Kubanych Usenov, Nikita Valuisky, Jiaying Wang, Vladimir Zarubaev
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Molecular diversity , 2025
• Bộ sưu tập: NCBI
• ID: 699823

Tóm tắt

A large series of 2-arylchromen-4-ones containing from 1 to 3 fluorine atoms or a trifluoromethyl group in the structure was synthesized by condensation of fluorinated 2-hydroxyacetophenones with benzaldehydes in an alkaline medium and subsequent oxidative cyclization of the resulting 2'-hydroxychalcones by action of I