Membrane progesterone receptor e (paqr9) is necessary for chorion elevation in zebrafish.

• Tác giả: Md Almamun Farid, Md Forhad Hossain, Akiteru Maeno, Takumi Mouri, Umme Habiba Mustary, Yuki Omori, Md Razain Tanvir, Toshinobu Tokumoto, Eisei Tsutsumi, Chihiro Yamamoto
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Fish physiology and biochemistry , 2025
• Bộ sưu tập: NCBI
• ID: 700435

Tóm tắt

Paqr9 is a gene encoding membrane progestin receptor e (mPRe), the fifth subtype of the five mPR subtypes, and is currently classified a member of the progestin and adipoQ receptor (PAQR) family, which consists of 11 genes. To elucidate the physiological functions of the mPR subtypes, we established gene knockout (KO) fish via genome editing of seven paqr genes in zebrafish and analyzed their phenotypes. The null-mutant strain of paqr9 (paqr9