Metabolic rewiring in skin epidermis drives tolerance to oncogenic mutations.

• Tác giả: Smirthy Ganesan, Daniel Gil, David G Gonzalez, Lauren E Gonzalez, Valentina Greco, Anupama Hemalatha, Elizabeth Lathrop, Zongyu Li, Catherine Matte-Martone, Rachel J Perry, Melissa Skala, Karen Tai
• Ngôn ngữ: eng
• Ký hiệu phân loại: 621.384196 Electrical, magnetic, optical, communications, computer engineering; electronics, lighting
• Thông tin xuất bản: England : Nature cell biology , 2025
• Bộ sưu tập: NCBI
• ID: 700820

Tóm tắt

 Skin epithelial stem cells correct aberrancies induced by oncogenic mutations. Oncogenes invoke different strategies of epithelial tolerance
  while wild-type cells outcompete β-catenin-gain-of-function (βcatGOF) cells, Hras