A comparative study on in vitro models of necrotizing enterocolitis induced by single and combined stimulation.

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Tác giả: Zongtai Feng, Kai Fu, Chuchu Gao, Lixia Wang, Sannan Wang, Zuming Yang, Shenglin Yu

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Egypt : Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 701073

BACKGROUND AND STUDY AIMS: Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease in neonates. In vitro model is an indispensable tool to study the pathogenesis of NEC. This study explored the effects of different stress factors on intestinal injury in vitro. MATERIAL AND METHODS: Rat intestinal epithelial cell line-6 (IEC-6) cells were exposed to different stressors, including lipopolysaccharide (LPS), cobalt chloride (CoCl RESULTS: The decrease in IEC-6 cell viability was observed after stimulation by CoCl CONCLUSION: The combined stimulation of LPS and CoCl
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