Response to functional restoration in non-specific chronic low back pain with Modic type 1 changes.

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Tác giả: Johann Beaudreuil, Agathe Clouzeau, Thomas Davergne, Louis Jacob, Marion Landais, Augustin Latourte, Odile Morchoisne, Agnès Ostertag, Léa Pavan, David Petrover, Pascal Richette, Jean-François Vergnol

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Germany : European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 701376

 PURPOSE: Little information exists on the potential differential response to functional restoration between non-specific chronic low back pain (NSCLBP) individuals with and those without Modic type 1 changes. Therefore, this case-control study investigated the response profile of NSCLBP patients with and without Modic type 1 changes undergoing functional restoration. METHODS: The present study included patients participating in a functional restoration program (day-hospital program lasting five weeks) at a French tertiary care center from 2009 to 2019. Each case with Modic type 1 changes was matched to one to two controls without Modic type 1 changes by sex, working incapacity, and lumbar spine surgery history. The primary effectiveness outcome was the Quebec Back Pain Disability Scale (QBPDS) score (0-100, with higher scores indicating higher disability). There were multiple secondary outcomes, such as subjective improvement and return to work. RESULTS: The study included 83 patients (cases: median [IQR] age 47.8 [11.6] years, 77.4% women
  controls: median [IQR] age 46.0 [16.2] years, 75.0% women). At three months, there were no statistically significant differences between cases and controls in the QBPDS score (34.0 versus 31.5), subjective improvement (67.7% versus 69.2%), return to work in those who were not working at the inclusion (72.7% versus 52.6%), and the consumption of different analgesics. CONCLUSION: The response profile of NSCLBP adults undergoing functional restoration did not statistically differ between the groups with and without Modic type 1 changes. These findings suggest that patients may benefit from such a program irrespective of their Modic type 1 status.
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