BackgroundBurnout and medical errors are the most prevalent issues affecting health and life outcomes among healthcare professionals.ObjectiveThis study aimed to investigate the longitudinal association between burnout and medical errors in healthcare workers in Japan.MethodsWe conducted a prospective cohort study involving 539 healthcare workers from January 2017 to January 2018. Burnout was evaluated using the Maslach Burnout Inventory-General Survey (MBI-GS), which included exhaustion, cynicism, and professional efficacy dimensions. Medical errors during the previous year were measured by self-assessment at follow-up. Multivariate modified Poisson regressions estimated the association between baseline burnout and follow-up medical errors.ResultsIn the age and sex-adjusted model, overall burnout was significantly associated with medical errors (