OBJECTIVE: To determine if performance on symptom, cognitive, balance, fatigue, physical activity, and quality of life outcomes at 4 weeks postinjury in children with concussion differs based on acute Predicting and Preventing Postconcussive Problems in Pediatrics (5P) risk classification. DESIGN: Prospective cohort. SETTING: Laboratory. PARTICIPANTS: Sixty-two children (age: 13.27±2.50y
29 [46.7%] women) with diagnosed concussion. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Patient demographics and postinjury assessments were completed within 72 hours of concussion and used to classify patients as "high," "moderate," or "low" persistent postconcussion symptoms risk. Children then completed a multimodal assessment battery at 4 weeks postconcussion. Kruskal-Wallis assessments analyzed whether study outcomes differed between 5P risk groups. RESULTS: Significant group differences were observed in symptom (χ CONCLUSIONS: The 5P rule provides clinicians with valuable prognostic information related to persistent postconcussion symptoms and self-reported outcomes 4 weeks postconcussion, but not objective cognitive or balance outcomes. This information may help clinicians prioritize treatment resources to children most at risk of prolonged concussion recovery.