Electrical and mechanical interventricular dyssynchrony coupling in patients with bradycardia: A UHF-ECG validation trial.

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Tác giả: Ahmed Beela, Karol Curila, Pavel Jurak, Pavel Leinveber, Hana Linkova, Jolana Lipoldova, Joost Lumens, Jan Mizner, Andrej Nagy, Frits Prinzen, Radovan Smisek, Petr Stros, Ondrej Sussenbek, Kevin Vernooy, Jana Vesela, Petr Waldauf

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : Heart rhythm , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 702988

 BACKGROUND: Ultra-high-frequency electrocardiography (UHF-ECG) is a noninvasive tool visualizing the ventricular activation sequence. It was never compared with other methods of dyssynchrony assessment in patients with bradycardia. OBJECTIVE: We aimed to compare UHF-ECG interventricular electrical dyssynchrony (e-DYS) with interventricular mechanical delay (IVMD) measured by echocardiography in patients receiving right ventricular pacing (RVP) or conduction system pacing (CSP). METHODS: Fifty-three patients with advanced atrioventricular conduction disease and preserved ventricular systolic function were prospectively assigned to RVP (n=32 [60 %]) or CSP (n=21 [40 %]). IVMD was measured as the time difference between left ventricular and right ventricular preejection periods. Interventricular e-DYS was calculated by software as the time difference between activation in V RESULTS: The median age of patients was 75 (interquartile range 72-80) years, and both groups had similar clinical characteristics. Baseline IVMD and interventricular e-DYS were similar in the entire population (-2 [-8 to 5] ms vs-1 [-6 to 5] ms, respectively
  P=.52). Both methods showed the same dyssynchrony trends after pacemaker implantation
  that is, while both IVMD and interventricular e-DYS increased in the RVP group (IVMD 28 [23-33] ms vs interventricular e-DYS 26 [19-33] ms
  P=.99), they remained low in the CSP group (IVMD -7 [-16 to 2] ms vs interventricular e-DYS -5 [-12 to 2] ms
  P=.91). There was a moderate overall correlation between IVMD and interventricular e-DYS for all studied ventricular rhythms (R=0.74). CONCLUSION: UHF-ECG noninvasively expresses interventricular dyssynchrony from V
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