The role of assessment in PharmD education and program accreditation continues to evolve with the release of the Curricular Outcomes and Entrustable Professional Activities (COEPA) and the Accreditation Council for Pharmacy Education Standards 2025. This special collection, titled the COEPA Curricular Assessment Blueprint and Needs Analysis, highlights best assessment practices related to each COEPA subdomain. The articles in this collection provide a blueprint for educators seeking a framework for designing and implementing assessment plans that achieve the expected outcomes for PharmD programs. The contributions of various authors in this collection are designed to offer guidance, inspiration, and suggestions to colleges and schools of pharmacy, as well as to promote analysis, evaluation, and debate that will advance pharmacy education and, ultimately, the pharmacy profession.