Effect of three different frequencies of micro-magnetic stimulation on the neuronal electrical activity of the hippocampal CA1 neurons in mice.

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Tác giả: Yazhou Chen, Lei Dong, Dejiao Qi, Chunxiao Tian, Meng Wang, Yu Zheng

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : Neuroscience , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 703259

Frequency is essential in regulating neuroelectric activity using magnetic fields. Current reports focus on 100 Hz or less. Studying other relatively high magnetic stimulation frequencies is necessary to reveal the influence of magnetic stimulation frequency parameters on electrical activity.This paper examined the pyramidal neurons in the CA1 region of the hippocampus of C57 mice. A custom-built micro-magnetic stimulation (μMS) device with sub-millimeter dimensions was utilized. Three magnetic field frequencies of 15 Hz, 3 kHz, and 70 kHz were chosen at a magnetic field strength of 1 mT. Precision-targeted magnetic stimulation of CA3 area neurons upstream of CA1 by whole-cell membrane clamp method. The effects of three various magnetic stimulation frequencies on the action potential (AP), sodium channel current (I
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