A cryptic pocket in CB1 drives peripheral and functional selectivity.

• Tác giả: Jhoan Aguilar, Kevin Appourchaux, Yaseen Awad-Agbaria, Deniz Aydin, Zachariah Bertels, Michael D Cameron, Ron O Dror, Jakayla Folarin-Hines, Robert W Gereau, Xi-Ping Huang, Anirudh Kalathil, Brian K Kobilka, Kaavya Krishna Kumar, Li Lin, Susruta Majumdar, Elizaveta Mangutov, Juliet Mwirigi, Evan S O'Brien, Maria Payne, Teja Nikhil Peddada, Alexander S Powers, Amynah A Pradhan, Nokomis Ramos-Gonzalez, Vipin Ashok Rangari, Yuki Shiimura, Richard A Slivicki, Briana L Sobecks, Manoj B Uphade, Balazs R Varga
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 703547

Tóm tắt

The current opioid overdose epidemic highlights the urgent need to develop safer and more effective treatments for chronic pain