Should lymphadenectomy be recommended in radical surgery of intrahepatic cholangiocarcinoma patients? A retrospective study.

• Tác giả: Dayong Cao, Bo Chen, Ning Huang, Mei Liu, Liming Wang, Min Yang, Feng Ye, Jiajun Zhang, Ruoyu Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 373.236 Lower level
• Thông tin xuất bản: Germany : Journal of cancer research and clinical oncology , 2025
• Bộ sưu tập: NCBI
• ID: 703627

Tóm tắt

PURPOSE: Intrahepatic cholangiocarcinoma (ICC) is an extremely deadly cancer with high recurrence incidence, particularly in patients with lymph node metastasis (LNM). The necessity of lymphadenectomy including lymph node biology (LNB) and dissection (LND) during ICC radical surgery remains debate. METHODS: We retrospectively analyzed the patients diagnosed with ICC and underwent radical surgery at the Cancer Hospital of the Chinese Academy of Medical Sciences from 2012 to 2023. RESULTS: A total of 308 ICC patients were involved in this study. pLNM CONCLUSION: Lymphadenectomy does not necessarily provide long-term survival or recurrence benefits. LND only achieves the effect of LNB while negatively affects postoperative recovery without survival benefit for ICC patients. LNB can be performed for accurate pathological staging while not all patients may require LND based on their specific circumstances.