An Oxymetazoline-Based Nasal Solution Removes Bacteria-Blood Debris on Dental Surfaces and Has Antimicrobial Activity Toward

• Tác giả: Robert S Jones, Dhiraj Kumar, Morgan Annina Pride
• Ngôn ngữ: eng
• Ký hiệu phân loại: 613.718 Stretching exercises, and exercises for muscles of specific parts of body
• Thông tin xuất bản: Switzerland : International journal of molecular sciences , 2025
• Bộ sưu tập: NCBI
• ID: 70374

Tóm tắt

BACKGROUND: An over-the-counter vasoconstrictive nasal solution with oxymetazoline (NS-OXY, 0.05%) has the potential to be used as a dental pulpal hemostatic medicament. A molecular engineering approach examined NS-OXY and its molecular constituent's antimicrobial and blood biomass removal efficacy. METHODS: An ex vivo cavity model was developed where standardized prepared teeth were exposed overnight to a model dentinal caries pathogen, RESULTS: NS-OXY-treated samples had a lower residual bacterial or blood biomass than FS ( CONCLUSIONS: NS-OXY may be considered as a dental hemostatic agent after traumatic and carious pulpal exposure owing to NS-OXY's antimicrobial and vasoconstrictive properties.