This study assessed the shear bond strength (SBS) and failure modes of lithium disilicate ceramic veneering material to different high-performance polymers. Thirty-six square specimens measuring 7 × 7 × 2 ± 0.05 mm were prepared from pure polyetheretherketone (PEEK), Bio-high performance PEEK (BioHPP) and Trilor discs. Polymer specimens were air-borne abraded utilizing aluminum oxide particles, cleaned, and a bonding agent was applied (visio. link). The veneering LDC material (3 × 2 mm) was milled, hydrofluoric acid etched (9.5%) and primed (Clearfil ceramic). The LDC was bonded to the polymer specimens using dual-cured resin cement (Panavia V5) and light polymerized. The bonded specimens were subjected to 5000 cycles of physiological aging by thermocycling, and the SBS test was performed in a universal testing machine at 0.5 mm/min cross-head speed. The debonded specimens were analyzed to determine the primary bond failure sites (adhesive, mixed or cohesive). Data analysis was performed using one-way ANOVA and a post hoc Tukey test (α ≤ 0.05). The BioHPP material demonstrated the highest SBS values (23.94 ± 1.43 MPa), and the Trilor group recorded the lowest SBS values (17.09 ± 1.07 MPa). The PEEK group showed a mean SBS of 21.21 ± 1.51 MPa. The SBS comparison showed significant variations across all material groups (