In Vitro Evaluation and Clinical Effects of a Regenerative Complex with Non-Cross-Linked Hyaluronic Acid and a High-Molecular-Weight Polynucleotide for Periorbital Treatment.

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Tác giả: Philippe Abdel-Sayed, Hanadi Sami Abuyousif, Lee Ann Applegate, Marco Cerrano, Michèle Chemali, Nathalie Hirt-Burri, Alexis E Laurent, Kelly Lourenço, Cíntia Marques, Alexandre Porcello, Wassim Raffoul, Corinne Scaletta

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Polymers , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 705039

Skin aging is a complex and multifactorial process influenced by both intrinsic and extrinsic factors. The periorbital area of the face is particularly susceptible to premature aging signs due to its delicate skin structure, and is a major concern for many individuals. While hyaluronic acid (HA)-based dermal filler products are commonly used for periorbital rejuvenation, novel approaches to effectively locally address the visible signs of aging are available. This study aimed to investigate Innovyal Regenerative Action (IRA), an injectable polynucleotide-HA (PN-HA) regenerative complex designed for periocular prejuvenation. Firstly, PN-HA was compared to other commercially available HA-based dermbooster products (Profhilo
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