27-Hydroxymangiferolic Acid Extends Lifespan and Improves Neurodegeneration in

• Tác giả: Shengjie Fan, Minglv Fang, Xiaoyan Gao, Cheng Huang, Yin Li, Ying Liu, Hang Shi, Jing Yu, Lijun Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 949.59012 *Greece
• Thông tin xuất bản: Switzerland : Molecules (Basel, Switzerland) , 2025
• Bộ sưu tập: NCBI
• ID: 705239

Tóm tắt

27-Hydroxymangiferolic acid (27-HMA) is a naturally occurring compound in mango fruits that exhibits diverse biological functions. Here, we show that 27-HMA activates the transcriptional activity of farnesoid X receptor (FXR), a nuclear receptor transcription factor, extending the lifespan and healthspan in