Novel Triazeneindole Antibiotics: Synthesis and Hit-to-Lead Optimization.

• Tác giả: Anna Emelianova, Alla Filimonova, Elena Guglya, Evgeniy Gusev, Artem Gvozd, Vadim Kublitski, Denis Kuzmin, Vladimir Shmygarev, Boris Sorokin, Ilia Yampolsky
• Ngôn ngữ: eng
• Thông tin xuất bản: Switzerland : International journal of molecular sciences , 2025
• Bộ sưu tập: NCBI
• ID: 705405

Tóm tắt

Bacterial antibiotic resistance represents a major healthcare problem. In 2019, 4.95 million deaths were associated with antibiotic resistance, and it is estimated that, by 2050, up to 3.8% of the global gross domestic product could be lost due to this problem. Methicillin-resistant