Cancer is a leading cause of death worldwide, characterized by uncontrolled cell growth and multiple mutations. Chemotherapy is often associated with harmful side effects, and cancer cells may become resistant through various mechanisms. New approaches, which are able to address both the toxicity and resistance issues of chemotherapy, are of primary importance in cancer research. Antimicrobial peptides (AMPs), naturally occurring molecules in the innate immune system of all living organisms, have a wide spectrum of cytotoxic activities against cancer cells and could be a promising alternative to actual chemotherapeutics. Here, we tested peptide fractions, rich in AMPs, extracted from the hemolymph of the larvae of the insect