Trastuzumab Decreases the Expression of G1/S Regulators and Syndecan-4 Proteoglycan in Human Rhabdomyosarcoma.

• Tác giả: Noemi Bozsity-Farago, Zsofia Kata Hegedus, Aniko Keller-Pinter, Laszlo Rovo, Dora Julianna Szabo, Kitti Szabo, Eniko Toth, Xue Xiao, Lin Xu, Istvan Zupko
• Ngôn ngữ: eng
• Thông tin xuất bản: Switzerland : International journal of molecular sciences , 2025
• Bộ sưu tập: NCBI
• ID: 705515

Tóm tắt

Rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, arises from skeletal muscle cells that fail to differentiate terminally. Two subgroups of RMS, fusion-positive and fusion-negative RMS (FPRMS and FNRMS, respectively), are characterized by the presence or absence of the