Acid Sphingomyelinase Regulates AdipoRon-Induced Differentiation of Arterial Smooth Muscle Cells via TFEB Activation.

• Tác giả: Jenny Z Hu, Pin-Lan Li, Xiang Li, Alexandra K Moura, Kiana Roudbari, Yun-Ting Wang, Zhengchao Wang, Yang Zhang, Wei Zhao, Rui Zuo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 597.95968 Reptilia (Reptiles)
• Thông tin xuất bản: Switzerland : International journal of molecular sciences , 2025
• Bộ sưu tập: NCBI
• ID: 705567

Tóm tắt

 AdipoRon is a selective adiponectin receptor agonist that inhibits vascular remodeling by promoting the differentiation of arterial smooth muscle cells (SMCs). Our recent studies have demonstrated that activation of TFEB and its downstream autophagy-lysosomal signaling contribute to adipoRon-induced differentiation of SMCs. The present study was designed to examine whether acid sphingomyelinase (ASM
  gene symbol