Novel Camptothecin Derivative 9c with Enhanced Antitumor Activity via NSA2-EGFR-P53 Signaling Pathway.

• Tác giả: Fu Du, Tao Jiang, Jing Li, Xin Qi, Ruijuan Yin, Aotong Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 780 Music
• Thông tin xuất bản: Switzerland : International journal of molecular sciences , 2025
• Bộ sưu tập: NCBI
• ID: 705597

Tóm tắt

 Therapeutic challenges persist in the management of non-small cell lung cancer (NSCLC) in oncology. Camptothecins have demonstrated as crucial agents in tumor therapy
  however, their efficacy is significantly hindered by adverse effects and drug resistance. Herein, we present a novel camptothecin derivative named