BACKGROUND: This study was conducted to determine the difference in clinical outcomes and satisfaction between men and women after total knee arthroplasty (TKA) and whether the relationship between postoperative outcomes and satisfaction differs between the 2 groups after TKA. MATERIALS AND METHODS: This retrospective study included 324 patients who underwent TKA. The participants were divided by sex as follows: male (n=130) and female (n=194). The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Knee Society Score (KSS), and satisfaction score and their correlation coefficients at 1 and 2 years after TKA were compared between the groups. RESULTS: The satisfaction scores of the male and female patients were 27.1 and 22.7, respectively ( CONCLUSION: The early postoperative satisfaction of female patients was lower than that of male patients but eventually improved to the satisfaction level of male patients, and the association between outcomes and satisfaction within 2 years after TKA was higher for female patients than for male patients. [