Single cell analysis reveals that SPP1

• Tác giả: Xiao Che, Hungchen Chen, Yixuan Chen, Zequn Chen, Chunhui Cui, Yingming Fan, Chengyu Huang, Junpeng Huang, Bingyao Li, Qingzhong Li, Ting Li, Xinyu Li, Ke Mo, Bowen Qiu, Junyao Shi, Haocheng Wang, Qian Wang, Qun Wang, Yue Wang, Ziying Wu, Yao Ying, Fanan Zeng
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Translational oncology , 2025
• Bộ sưu tập: NCBI
• ID: 708064

Tóm tắt

Patients with liver metastatic colorectal cancer (mCRC) have a poor prognosis and are the leading cause of death in colorectal cancer (CRC) patients, but the mechanisms associated with CRC metastasis have not been fully elucidated. In this study, we obtained data from the Gene Expression Omnibus database and characterized the single-cell profiles of CRC, mCRC and healthy samples at single-cell resolution, and explored the cells that influence CRC metastasis. We find that AQP1