The widespread distribution and ecumenical abundance of the poultry red mite, Dermanyssus gallinae (De Geer), in chicken houses, has been bringing about one intractable challenge for the egg-laying hens. However, because of the appearance of drug resistance and the animal safety legislation, the search for some effective insecticidal agents is necessary. In the present investigation, the essential oil extracted from the tender shoots and young leaflets of Toona sinensis (Chinese toon, TSEO) were demonstrated to be not only display significant antioxidant effect, but also revealed prominent insecticidal activity against the poultry red mite. Briefly, in contact toxicity bioassay, the LC