Stevens-Johnson Syndrome is a rare disorder of the skin and mucous membranes accompanied by systemic symptoms that are life threatening and require immediate intervention. We sought to determine if different hospital types, specifically urban nonteaching hospitals versus urban teaching hospitals, have different outcomes among patients presenting with Stevens-Johnson Syndrome during hospitalization. Patients presenting to urban teaching and urban nonteaching hospitals were compared. Compared to patients at urban nonteaching hospitals, patients at urban teaching hospitals had significantly increased risk of mortality, and urban nonteaching hospitals had higher rates of transferring patients to another hospital. Future research is needed to explore patient outcomes beyond the hospitalization period and in different hospital settings.