AIM: The primary objectives of this study were to explore ICU and Tele-ICU nurses' perceptions of Tele-ICU, focusing on its perceived benefits, challenges, and implications for integration into critical care settings. BACKGROUND: Tele-Intensive Care Unit (Tele-ICU) services are reshaping critical care by enabling remote monitoring and enhancing patient outcomes. This study investigates the experiences of nurses transitioning from bedside ICU to Tele-ICU roles, focusing on the impact on patient care, organizational benefits, and implementation challenges. METHODS: A qualitative approach was used, involving semi-structured interviews with ICU nurses who transitioned to Tele-ICU roles. An interview guide was developed to explore key topics, including the benefits, challenges, and future implications of TeleICU. Thematic analysis was applied to identify recurring themes and subthemes. RESULTS: Participants highlighted several benefits of Tele-ICU, including continuous patient monitoring, improved infection control, and enhanced resource utilization. Organizational advantages included reduced length of stay, lower readmission rates, and improved post-discharge planning. However, significant barriers were identified, such as technological infrastructure issues, financial constraints, resistance to workflow changes, and gaps in training. Cultural preferences for in-person care and regulatory challenges were also noted. CONCLUSIONS: Tele-ICU presents significant opportunities to improve critical care delivery, but its success depends on addressing implementation barriers. Investments in technology, comprehensive training, and supportive policies are essential for maximizing its potential and facilitating broader adoption in healthcare settings.