Age-dependent influence of T wave amplitude on short period temporal dispersion in healthy subjects.

• Tác giả: Cristina Caltabiano, Giovanni Cisaria, Valerio De Santis, Giovambattista Desideri, Marco Giuffrè, Ilaria Lospinuso, Martina Mezzadri, Federica Moscucci, Gianfranco Piccirillo, Pietro Rossi, Claudia Scinicariello, Susanna Sciomer, Sara Stefano, Guendalina Vizza
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Journal of electrocardiology , 2025
• Bộ sưu tập: NCBI
• ID: 709860

Tóm tắt

 BACKGROUND: T wave amplitude and repolarization variability in ECG showed inverse correlations. Sympathetic activation, induced by head-up tilt, is associated to a reduced T wave amplitude. METHODS: Noninvasive hemodynamic and ECG data from three healthy subjects' groups (Group 1: 10-19 years-old
  Group 2: 40-49 years-old
  Group 3: 80-89 years-old) were analyzed. Measurements were taken during controlled-breathing rest, and during head-up tilt. The mean and standard deviation ( RESULTS: During tilt, a significant decrease in T wave amplitude was observed in the younger groups (p <
  0.001), but not in Group 3. At rest, Group 1 exhibited higher voltage compared to Group 2 (p <
  0.05) and 3 (p <
  0.001), as Group 2 compared to Group 3 (p <
  0.05). A negative correlation was confirmed between T wave amplitude and QT CONCLUSION: The findings suggest an age-dependent decline in T wave amplitude during tilt and elucidates the relationship between systolic function and T wave amplitude among healthy subjects. These insights warrant further investigations in clinical and research settings for cardiovascular diseases.