Mitochondria-Targeted Temozolomide Probe for Overcoming MGMT-Mediated Resistance in Glioblastoma.

• Tác giả: Shana O Kelley, Daniel Szames
• Ngôn ngữ: eng
• Ký hiệu phân loại: 722.33 *Ancient Palestinian architecture
• Thông tin xuất bản: Germany : Chembiochem : a European journal of chemical biology , 2025
• Bộ sưu tập: NCBI
• ID: 710165

Tóm tắt

Temozolomide (Tmz) is a DNA methylating agent used for the treatment of glioblastoma multiforme (GBM). Resistance to Tmz in GBM is caused by the DNA direct repair enzyme O