BACKGROUND & OBJECTIVES: No validated questionnaires exist to examine the public's attitudes about epilepsy in Arabic in particular. Therefore, this study aimed to test the validity and reliability of the Arabic version of the Public Attitudes Toward Epilepsy (PATE) scale. METHODS: In this cross-sectional study, Egyptian Arabic-speaking adults aged >
18 from different socioeconomic backgrounds were enrolled. To capture the factor structure of the items, exploratory factor analysis was performed using Equamax rotation with Kaiser Normalization. The reliability of the scale was tested by measuring Cronbach's alpha. RESULTS: Five hundred sixty participants (205 males and 355 females) with a median age of 33 (25-41) years were enrolled. Cronbach's alpha was 0.806 for the general domain, indicating excellent reliability, while it was 0.644 for the personal domain, indicating satisfactory reliability. No ceiling or floor effects were detected. Also, the correlation coefficients between each item and its corresponding domain were higher than that of the other domain or the total score. Exploratory factor analysis confirmed that items on the PATE scale were loaded on their two hypothesized domains. CONCLUSION: The Arabic version of the PATE scale is a valid and reliable tool for assessing the attitudes toward epilepsy in Arabic-speaking populations.