Combination locoregional and systemic therapies in hepatocellular carcinoma.

• Tác giả: Jian-Jian Chen, Wenzhe Fan, Justin J Guan, Zhongzhi Jia, Haojie Jin, Zhi-Cheng Jin, Zhenwei Peng, Gao-Jun Teng, Bin-Yan Zhong, Hai-Dong Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 579.89 *Rhodophyta (Red algae)
• Thông tin xuất bản: Netherlands : The lancet. Gastroenterology & hepatology , 2025
• Bộ sưu tập: NCBI
• ID: 710588

Tóm tắt

Locoregional therapies play a fundamental role in the treatment of patients with early and intermediate and locally advanced hepatocellular carcinomas. With encouraging recent advances in immunotherapy-based systemic therapies, locoregional therapies are being both promoted and challenged by new systemic therapy options. Combined locoregional and systemic therapies might enhance treatment outcomes compared with either option alone. This Series paper summarises the existing data on locoregional and systemic therapies for hepatocellular carcinoma, and discusses evidence from studies investigating their combination with a focus on their synergistic efficacy and safety.