One-dimensional (1D) Pd-based nanowire materials, characterized by high aspect ratios and exposed high-index crystal surfaces, are widely developed in the field of direct fuel cells. However, their synthesis methods are often not universal and necessitate demanding conditions, including high temperatures and metal templates, leading to resource consumption. In this study, we present a simple and universal one-step method for synthesizing PdM (Sb, Ir, and Bi) nanowire networks (NNWs) at room temperature. Leveraging their structural advantages and the synergistic effects between bimetals, PdM NNWs demonstrate exceptional electrocatalytic performance, exhibiting higher mass and specific activities as well as enhanced durability compared to Pd/C for the ethylene glycol and glycerol oxidation reactions. Notably, PdSb NNWs excelled in electrochemical tests, achieving the highest mass activities of 7.55 and 5.59 A mg